Antifungals are drugs used to treat infections caused by fungi, including yeasts and molds. The classes of antifungal drugs currently on the market include: 1) Antifungals that alter the cell membrane. From the chemical point of view, these antifungal drugs are polyenes, ie they are aliphatic hydrocarbons containing numerous carbon-carbon double bonds within their chemical structure. 2) Inhibitors of ergosterol biosynthesis. These drugs act by inhibiting one of the key enzymes of ergosterol synthesis, 14α-demethylase; 3) Biosynthesis inhibitors of the fungal cell wall. These antifungal agents inhibit one of the enzymes involved in the synthesis of the fungal cell wall, β-1,3-glucan synthase.
Diflucan is an oral drug used in treatment of vaginitis and balanitis caused by Candida albicans, as well as cutaneous mycoses (tinea pedis, tinea corporis, tinea cruris and pityriasis versicolor). Continue reading