Alesse

Basic Drug Info

Manufacturer: Amneal Pharmaceuticals LLC
Active Substance: Levonorgestrel and ethinyl estradiol
Drug Form: Film-coated tablets
Available Doses: Levonorgestrel 0.10mg and ethinyl estradiol 0.02mg

active substance Levonorgestrel and ethinyl estradiol

What is Alesse

Alesse (other brand names: Amethyst, Aviane, Balcoltra, Loette, Orsythia an others) is a combined contraceptive for oral use. Each tablet contains two different female hormones: levonorgestrel and ethinyl estradiol. Since all the tablets in the pack contain the combination of the same hormones in the same dose, the product is considered a combined monophasic oral contraceptive.

How long until Alesse birth control is effective

Alesse is a monophasic pill. It must be taken on the first day of menstruation and followed every day at the same time, until the package is used up. If the patient starts on Wednesday she will take the tablet on the first Wednesday and continue for the next 20 days, ending the Wednesday of the third week. During the 7 days after the last tablet, a small suspension bleeding will appear. After these seven days of break you start with a new box. Alesse becomes effective after 7 cnosecutive days of use.

Why was Alesse discontinued?

In the U.S., Alesse was discontinued as a brand name medication, but Alesse generic is still available produced by the manufacturer Amneal Pharmaceuticals LLC. The generic version of the drug is fully equivalent to that of the original drug, with safety and efficacy being interchangeable with those of the brand pill.

What is Alesse used for?

Alesse is a contraceptive pill, containing ethinyl estradiol (0.02 mg) as estrogen and levorgestrel (0.1 mg) as a progestin. Each box contains a blister pack with 21 tablets. Next to each tablet are indicated the days of the week, in continuous sequence for three weeks.

Alesse is a contraceptive preparation indicated for the prevention of conception in women of childbearing age. As with all birth control pills, contraceptive protection is due to the inhibition of ovary release by the ovary. In addition, the contraceptive effect is also expressed through the formation of a denser cervical mucus, more difficult to pass through by spermatozoa, and by modifications of the endometrium (the mucous membrane of the uterus).

Side effects

The most frequent side effects include, headache, depressed mood, menstrual disorders, increased blood pressure (hypertension), increased blood sugar, water retention etc. For a complete list of contraindications, side effects and interference with other drugs, consult your doctor. For more information, read Alesse’s package insert.

Precautions

In the presence of any of the conditions listed below, the use of the combined type pill may require close supervision by the physician. It is therefore necessary to warn the doctor of the presence of any of the above conditions before starting to use Alesse. Your doctor may recommend a completely different method of contraception (non-hormonal).

  • Smoking;
  • Diabetes;
  • Overweight;
  • Hypertension (see “Special warnings”);
  • Heart valve defects or some heart rhythm disorders;
  • Superficial phlebitis (venous inflammation);
  • Varicose veins;
  • Migraine;
  • Depression;
  • Epilepsy;
  • High levels of cholesterol and triglycerides (fats) in the blood, present or past, even in close family members (see “Special warnings”);
  • Breast lumps;
  • Previous, in next family members, of breast cancer;
  • Diseases of the liver or gallbladder (see “Special warnings”);
  • Crohn’s disease or ulcerative colitis (chronic inflammatory bowel disease);
  • Systemic lupus erythematosus (a disease that affects the skin of the whole body);
  • Hemolytic-uremic syndrome (blood clotting disorder that causes renal failure);
  • Sickle cell disease;
  • Porphyria;
  • Chloasma, present or previous (patches on the skin with yellowish-brown pigmentation, in particular on the face). In this case, avoid prolonged exposure to the sun or ultraviolet rays;
  • Previous herpes gestationis;
  • Some pathological conditions characterized by resistance to activated protein c, hyperhomocysteinemia, antithrombin iii deficiency, protein c deficiency, protein s deficiency, antiphospholipid antibody syndrome (anticardiolipin antibodies, lupus anticoagulant), which predispose to venous or arterial thrombosis ;
  • Sydenham chorea (central nervous system disorder);
  • Hearing loss from otosclerosis.

In case of first occurrence, recurrence or worsening of any of the above conditions while using the pill, consult your doctor.

Preparations based on Hypericum perforatum should not be taken concomitantly with medicinal products containing oral contraceptives, digoxin, theophylline, carbamazepine, phenobarbital, phenytoin due to the risk of decreased plasma levels and decreased therapeutic efficacy of oral contraceptives, digoxin, theophylline, carbamazepine, phenobarbital, phenytoin

Contraindications

The contraindications and tests to be performed before starting to take Alesse are the classic ones of all birth control pills. In addition to hypersensitivity to the active ingredients or to one of the excipients, Alesse is contraindicated in women with previous cardiac infarct, cerebral stroke, venous thromboembolic disease, diabetes with associated peripheral vasculopathy, ophthalmic vascular disease or hereditary predisposition for arterial or venous thrombosis. The risk of arterial thrombosis increases in women smokers after the age of 35.

Analogs

Amethyst, Aviane, Balcoltra, Falmina, Levlen, Lillow, Loette, Orsythia, Vienva

Posted in Birth Control
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